P6466Clinical efficacy of the external counterpulsation therapy in patients with stable coronary artery disease and obstructive sleep apnea
European Heart Journal, Volume 38, Issue suppl_1, 1 August 2017, ehx493.P6466,https://doi.org/10.1093/eurheartj/ehx493.P6466
Published: 29 August 2017
Purpose: The goal of the study was to assess the efficacy of external counterpulsation (ECP) therapy in patients (pts.) with stable coronary artery disease (CAD) and severe obstructive sleep apnea (OSA).
Methods: Open, non-controlled clinical study. Forty five (n=45) stable CAD with limiting angina (CCS, functional class II-III) and severe OSA (RDI>30 events/h) subjects (41 male and 4 female; mean age 65±13,4) received 35 hours ECP-treatment (250–300 mm Hg) course (5±2 one-hour ECP sessions per week; 5–7 weeks). All subjects refused of the CPAP-therapy. At baseline, immediately after ECP course, 6 months and 1 year after ECP course every subject was examined with exercise stress test, echocardiography, Holter monitoring (24h) and cardiorespiratory pulse arterial tonometry (PAT) monitoring during nighttime sleep.
Results: 100% of pts. improved >1 angina class (CCS),.
